The functional response of rat skeletal muscle to fasting, underfeeding, and refeeding

a role for diet composition in recovery.

Publisher: National Library of Canada in Ottawa

Written in English
Published: Downloads: 376
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Edition Notes

Thesis (M.Sc.)--University of Toronto, 1990.

SeriesCanadian theses = Thèses canadiennes
The Physical Object
FormatMicroform
Pagination3 microfiches.
ID Numbers
Open LibraryOL14890992M
ISBN 100315585080
OCLC/WorldCa31289978

  The purpose of this study was to determine the impact of exercise with and without carbohydrate supplementation on skeletal muscle metabolic response in the heat. Methods Eight recreationally active males ( ± L. min -1) completed 2 trials which included 1 hr of cycling at 70% workload max and 3 hr recovery in a hot by: 3. effective models for studying growth, cellular development of skeletal muscle and body composition. Bradford () discovered that weight gain in mice from days in age was nearly doubled by 23 generations of selection for this trait. Baker and Chapman () found that the selection for week gain in rats resulted in a marked increase in. Physiology of Intermittent Feeding: Integrating Responses of (adipose, muscle, skeletal) may be involved at different time-scales (from seconds to months). Most information on nutrient sumed minimal delay between feeding or fasting and their ef-fects on energy and . Only a limited number of studies have compared skeletal muscle gene expression of lean and obese dogs. The objective of study 3 was to identify genes and functional classes differentially expressed between lean and obese dog skeletal muscle at 24 wk of the animal experiment described in study : Ryan W. Grant.

Nutrition Module 3. STUDY. PLAY. metabolism. the sum total of all the chemical reactions that go on in living cells. after a hour fast and restful sleep, without any physical activity or emotional excitement, and in a comfortable setting; usually expressed as kcalories per kilogram of body weight per hour death of a heart muscle. Refeeding Syndrome •The metabolic and hormonal changes caused by rapid refeeding. •Protein and fat as main energy source •BMR reduces by •Muscle and tissues decrease use of ketone bodies – fatty acids as energy source. •Brain –uses ketones as main energy source. •Liver –reduces rate of Size: KB. Nutrients, an international, peer-reviewed Open Access journal.   Two weeks ago, I embarked on what is widely considered the extreme smart bomb of the diet world: the protein sparing modified fast. A protein sparing modified fast (psmf) is essentially the most scientific “crash diet” available, allowing the loss of 4 to 7 pounds of fat and 10 to 20 lbs of weight in 2 .

Stangel M, Zettl UK, Mix E, Zielasek J, Toyka KV, Hartung HP, Gold R: H2O2 and nitric oxide-mediated oxidative stress induce apoptosis in rat skeletal muscle myoblasts. J Neuropathol Exp Neurol ;– Berg HE, Tesch PA: Changes in muscle function in response to 10 days of lower limb unloading in humans. Welcome to F.E.A.S.T's Around The Dinner Table forum. This is a free service provided for parents of those suffering from eating disorders. It is moderated by kind, experienced, parent caregivers trained to guide you in how to use the forum and how to find resources to help you support your family member. This forum is for parents of patients. ABSTRACT: Repetitive eccentric contractions are associated with repetitive strain injury (RSI) of muscle and tendon and were accompanied by an increase in extracellular matrix (ECM), atrophy, and reduce force. However, a research gap exists regarding the effect of aging on injury susceptibility and recovery to repetitive strain exposures. In this paper, we examined the response of. response, the host has developed a complex series of defense mechanisms that function together to prevent potentially pathogenic bacteria from adhering to the intestinal mucosa. These defense mechanisms of the gut barrier provide four generalized levels of protection: the stabilizing influence of the normal intestinal bacterial.

The functional response of rat skeletal muscle to fasting, underfeeding, and refeeding Download PDF EPUB FB2

Effects of Fasting, Refeeding, and Fasting With T3 Administration on Na-K,ATPase in Rat Skeletal Muscle Masako Matsumura, Nobuaki Kuzuya, Yasushi Kawakami, and Kamejiro Yamashita It is known that Na-K,adenosine triphosphatase (ATPase) in cell membranes represents an important consumer of cellular energy, eg, adenosine triphosphate (ATP), and that the concentration and activity of this Cited by: This study determined whether an acute alcohol dose could inhibit the refeeding response in starved muscle.

Rats starved for 24 h were pretreated with alcohol or saline before refeeding by intragastric or intravenous infusion of enteral diet (ENT), total parenteral nutrition (TPN), or saline.

An early specific effect of carbohydrate refeeding was an increase in the insulin response in glucose metabolic pathways in adipose tissue. Inhibiting carbohydrate absorption by a glucosidase inhibitor (Acarbose) caused a delay in energy accumulation during refeeding both in glycogen stores, and, more markedly, in adipose tissue triglyceride by: Skeletal muscle fiber is largely classified into two types: type 1 (slow‐twitch) and type 2 (fast‐twitch) fibers.

Meat quality and composition of fiber types are thought to be closely related. The postoperative reduction in insulin sensitivity is similar to that seen in other conditions associated with insulin resistance such as type 2 diabetes and ageing.1, 6 Studies on patients with these conditions suggested a link between the development of insulin resistance and impaired mitochondrial function in skeletal muscle.1, 7, 8 Compared to younger controls, elderly insulin-resistant subjects had a 40% reduction in the basal rates of muscle mitochondrial Cited by: Because skeletal muscle accounts for 65–90% of glucose clearance during a hyperglycemic challenge (10, 15, 18), insulin signaling in skeletal muscle has been a major focus of the adaption to interventions aimed at improving insulin sensitivity.

However, nutritive blood flow to metabolically active tissue is an important component of insulin Cited by:   The present study investigated the effects of fasting and refeeding on the expression of proteasome-related genes and their downstream targets in the skeletal muscles of chicks. Seven-day-old chicks were fasted for 24 or 48 h and then refed for 4 by: 9.

The role of USF in the insulin response was suggested by Casado et al., who showed that germ line knockout of either USF-1 or USF-2 largely blocked the induction of FAS transcription in a fasting-refeeding protocol.

Considered together with the data in the SCAP-deficient mice, these data indicate that nuclear SREBPs are both necessary and.

repeated fasting-refeeding experiments in humans, animal experiments have been conducted to investigate effects on lipid and carnitine profiles. In this research, we used five groups of mice: one fed a normal diet while the others were subjected to fasting, and fasting-refeeding repeated once, twice, and three times, respectively.

tion from skeletal muscle.3 Other adaptive mecha-nisms include an overall decrease in liver gluconeo-genesis, a decline in basal metabolic rate, reduction in the secretion of insulin, and an increased use of free fatty acids by the brain as the primary energy source in place of glucose.

Refeeding With the reintroduction of carbohydrate via oralFile Size: KB. Reduced mitochondrial capacity in skeletal muscle has been observed in obesity and type 2 diabetes. In humans, the aetiology of this abnormality is not well understood but the possibility that it is secondary to the stress of nutrient overload has been suggested.

To test this hypothesis, we examined whether sustained overfeeding decreases skeletal muscle mitochondrial content or impairs by: 2.

RESEARCH Open Access Plasticity of adipose tissue in response to fasting and refeeding in male mice Hao-Neng Tang1,2, Chen-Yi Tang1, Xiao-Fei Man1, Shu-Wen Tan1, Yue Guo1, Jun Tang1, Ci-La Zhou1 and Hou-De Zhou1* Abstract Background: Fasting is the most widely prescribed and self-imposed strategy for treating excessive weight gainCited by:   Translational regulation of protein synthesis in the liver and skeletal muscle of mice in response to by: skeletal muscle,7 liver,8 and adipose tissue6 from GK rats fed a normal rodent diet (10% fat) which demonstrated elevated chronic inflammation due to heightened natural immunity in all 3 tissues.

In additional studies, we compared those diabetic and con-trol animals fed a normal rat. Weanling rats were fed on a diet planned to resemble that eaten by poor people in Jamaica; it contained per cent. protein and per cent.

carbohydrate. One group were killed after 4 weeks and the rest were transferred for different periods to a stock diet with 18 per cent. protein. On the Jamaican diet growth almost ceased.

Bodyweight and weights of liver and muscle remained the same as Cited by:   The present study set out to determine the temporal responses of protein synthesis in the skeletal muscle of healthy subjects to the consumption of food. Sequential measurements of protein synthesis in quadriceps muscle were made in eight subjects by injection of g L-[l- Cited by:   The phenotypes of adipose tissues between juvenile and adult mice subjected to fasting and refeeding were also compared.

Fasting preferentially consumed mesenteric fat mass and decreased the cell size of mesenteric depots; however, refeeding recovered the mass and morphology of inguinal adipose tissues preferentially compared with visceral by: Understanding the bone metabolic response to exercise following fasting and feeding is important, since the practice of periodic fasting, be it for training, health or indeed cultural or religious purposes [39], might influence the risk of skeletal injury and longer-term bone Size: 2MB.

To investigate the effects of dietary crude protein (CP) restriction on muscle fiber characteristics and key regulators related to protein deposition in skeletal muscle, a total of 18 growing-finishing pigs ( ± kg) were allotted to 3 groups and fed with the recommended adequate protein (AP, 16 % CP) diet, moderately restricted protein (MP, 13 % CP) diet and low protein (LP, 10 % CP Cited by: A role for FGF-6 in skeletal muscle regeneration.

Thomas Floss, of double mutants that are likely to result from compensatory growth factor circuits built up in response to continuous damage of skeletal muscle in mdx mice (Stedman et al MyoD is required for myogenic stem cell function in adult skeletal muscle. Impact of cafeteria feeding during lactation in the rat on novel object discrimination in the offspring - Volume Issue 12 - Thomas M.

Wright, Madeleine V. King, William G. Davey, Simon C. Langley-Evans, Jörg-Peter W. VoigtCited by: 8. The Effect of Exercise on the Skeletal Muscle Phospholipidome of Rats Fed a High-Fat Diet Todd W.

Mitchell 1,*, Nigel Turner 2, Paul L. Else 1, Anthony J. Hulbert 3, John A. Hawley 4, Jong Sam Lee 5, Clinton R. Bruce 6 and Stephen J. Blanksby 7 1 School of Health Sciences, University of Wollongong, NSWAustralia; E-Mail: [email protected]   An inducible form of NOS (iNOS) has been found in skeletal muscle, and its induction can lead to increase of oxidative stress response in skeletal muscle tissue.

Muscle proteins can be oxidatively damaged and the activation of an energy-independent proteolytic pathway accelerates muscle protein degradation (). The rate of protein synthesis (Ks) was measured in nine skeletal muscles from young rats ( g body wt) after fasting and subsequent insulin infusion.

An overnight fast (12 h) resulted in a fall in Ks in all muscles, but this ranged from a small nonsignificant decrease in soleus (Sol) to one-half of the fed rate in tensor fascia latae (TFL).Cited by: The IL-1β response of monocytes from individual subjects, comparing fasting to 3 hours following refeeding in response to ATP stimulation without prior priming, is shown in Figure 3A.

In parallel with the IL-1β effect and independent of exogenous priming, IL secretion was similarly induced 3 hours after refeeding (Figure 3B). Ehrenborg E, Krook A. Regulation of skeletal muscle physiology and metabolism by peroxisome proliferator-activated receptor δ Pharmacol Rev.

; – Escher P, Braissant O, Basu-Modak S, Michalik L, Wahli W, Desvergne B. Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.

by: 9. As you can see muscle glycogen / carb stores were the same in both groups at the beginning. And amazingly the low carb athletes replenished carb stores equally as fast as the high carb group following exercise. This brings into question the need to carb up on the weekends when ketogenic dieting.

If you are refeeding because the rest of the time you are both low kcal and liw carb, then the most effective refeeding (for leptin) will be one low fat, moderate protein, high starchy carb and/or glucose but low fructose. Skeletal muscle metabolic adaptations in response to an acute high fat diet Suzanne Mae Bowser ABSTRACT Macronutrient metabolism plays an essential role in the overall health of an individual.

Depending on a number of variables, for example, diet, fitness level, or metabolic disease state, protein, carbohydrate and fat have varying capacities to be. The ability of skeletal muscle to adapt and respond to various nutrient states is critical to maintaining healthy metabolic function.

Habitual high fat intake has been associated with reduced oxidative capacity, insulin resistance, increased gut permeability, inflammation, and other risk factors often preceding metabolic disease : Suzanne Mae Bowser.

Agreement between student dietitians' identification of refeeding syndrome risk with refeeding guidelines, electrolytes and other dietitians: a pilot study Matthews et al., JHND Early View Background Limited research exists concerning how consistently and accurately student and newly-graduated dietitians are identifying refeeding syndrome risk in hospitalised patients.Food availability regulates basal metabolism and progression of many diseases, and liver plays an important role in these processes.

The effects of food availability on digital gene expression profile, physiological and pathological functions in liver are yet to be further elucidated.

In this study, we applied high-throughput sequencing technology to detect digital gene expression profile of. The objective was to evaluate the muscle glucose metabolism in rats fed a fructose-rich diet after fetal protein malnutrition, at rest and after acute physical exercise at maximal lactate steady-state intensity.

The male offspring born of mothers fed on a balanced or low-protein diet were split in four groups until 60 days: Balanced (B): balanced diet during the whole period; Balanced/Fructose Author: Lucieli Teresa Cambri, Lucieli Teresa Cambri, Carla Ribeiro, Jose Diego Botezelli, Ana Carolina Ghez.